https://www.auroraoncology.com/story daily 0.75 2020-10-27 https://www.auroraoncology.com/story/6754321-6n7ej-jhm6t-4yefd-swm6s-42skp-ysynz-csgme-z62xg-r5ze6 monthly 0.5 2020-12-02 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f989419fc086a1d84819809/1603834923566/Screen+Shot+2020-10-27+at+3.40.51+PM.jpg Our Story - Won Park heads Aurora’s Nano research. - Did you know? Our team has used nanoparticles targeted to the EGF receptor to eliminate bladder cancer in a mouse model. https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f989142f8d2f740b7292c02/1603834320887/Screen+Shot+2020-10-27+at+3.28.27+PM.jpg Our Story - Won Park heads Aurora’s Nano research. Dr. Wounjhang (Won) Park Sheppard Professor and Associate Chair for Research Department of Electrical, Computer & Energy Engineering Materials Science & Engineering Program Biomedical Engineering Program University of Colorado Boulder https://www.auroraoncology.com/story/6754321-6n7ej-jhm6t-4yefd-swm6s-42skp-ysynz-csgme-z62xg-r5ze6-rzr45 monthly 0.5 2020-12-02 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f988971f8d2f740b727645a/1603832454907/Screen+Shot+2020-10-27+at+2.55.47+PM.jpg Our Story - Tom Flaig, MD Chairs the NCCN Bladder Panel. - About NCCN The National Comprehensive Cancer Network® (NCCN®) is a not-for-profit alliance of 30 leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to improving and facilitating quality, effective, efficient, and accessible cancer care so patients can live better lives. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f64cef235a29871a3864818/1600390712815/brooke-cagle-JBwcenOuRCg-unsplash.jpg Our Story - Tom Flaig, MD Chairs the NCCN Bladder Panel. - Did you know? The American Cancer Society’s estimates for bladder cancer in the United States for 2020 are: About 81,400 new cases of bladder cancer (about 62,100 in men and 19,300 in women) About 17,980 deaths from bladder cancer (about 13,050 in men and 4,930 in women) The rates of new bladder cancers and deaths linked to bladder cancer and have been dropping slightly in women in recent years. In men, incidence rates have been decreasing, but death rates have been stable. Bladder cancer is the fourth most common cancer in men, but it's less common in women. https://www.auroraoncology.com/story/6754321-6n7ej-jhm6t-4yefd-swm6s-42skp-ysynz-csgme-z62xg-r5ze6-y2anz monthly 0.5 2020-12-02 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f64cf3baf066d7b0adab0ca/1600390712815/brooke-cagle-JBwcenOuRCg-unsplash.jpg Our Story - The CU Anschutz Campus. - Did you know? The University of Colorado Anschutz Medical Campus has been awarded $4 million over the next four years from the National Institutes of Health (NIH) Research Evaluation and Commercialization Hubs (REACH) grant. As a result, the university is now part of a national network of research institutions sharing best practices around commercialization of academic discoveries. https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f988560095b317714ee68d2/1603831241072/Screen+Shot+2020-10-27+at+2.38.18+PM.jpg Our Story - The CU Anschutz Campus. The University of Colorado Anschutz Medical Campus is the academic health sciences campus in Aurora, Colorado that houses the University of Colorado's six health sciences-related schools and colleges. Aurora Oncology’s offices are located in the Bioscience I building on campus allowing close collaboration with the University’s faculty. https://www.auroraoncology.com/team daily 0.75 2021-01-12 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f724b9fd5c3655113d81791/1601325987356/mike.jpeg Meet the Team https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f724bcaa5850a6d52ff875e/1601326032625/richard.jpeg Meet the Team https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f85a1d57bd95c743b6399ec/1602593247297/Screen+Shot+2020-10-11+at+9.16.02+PM.jpg Meet the Team https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f85a1f34e506037d560fef6/1602593273897/shawn.jpeg Meet the Team https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f724be572c3ec4869ce6302/1601326063044/shawn.jpeg Meet the Team https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f85a1e70a9c2a5e6f2a7af1/1602593259359/Screen+Shot+2020-10-11+at+9.41.17+PM.jpg Meet the Team https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f640537e0a19475b6919b59/1589768312625/ Meet the Team https://www.auroraoncology.com/contact daily 0.75 2020-12-02 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f640547e0a19475b6919d1b/1589768312625/ Contact https://www.auroraoncology.com/home daily 1.0 2020-12-02 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f67addd9c2b2577e3b391ad/1600630242924/artificial-intelligence.png Home https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f862caf39e5dd37970eb074/1602628795646/molecule-2.png Home https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f64cbab0a02f049d75688b3/1600441281836/ Home - Multifunctional nanoclusters of NaYF4:Yb3+,Er3+upconversion nanoparticle and gold nanorod for simultaneous imaging and targeted chemotherapy of bladder cancer Suehyun K.Cho, Lih-JenSu, Chenchen Mao, Connor D.Wolenski, Thomas W.Flaig, Wounjhang Park https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f64cb8494d3c43a76a1782b/1600441235990/ Home - Diphtheria Toxin–Epidermal Growth Factor Fusion Protein DAB389EGF for the Treatment of Bladder Cancer Xiaoping Yang, Elizabeth Kessler, Lih-Jen Su, Andrew Thorburn, Arthur E. Frankel, Yuan Li, Francisco G. La Rosa, Jingping Shen, Chuan-Yuan Li, Marileila Varella-Garcia, L. Michael Glodé and Thomas W. Flaig DOI: 10.1158/1078-0432.CCR-12-1258 Published January 2013 https://www.auroraoncology.com/about daily 0.75 2020-12-02 https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f9aeec63ada5f54efc1f500/1603989194670/Picture2.png About https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f9475d925957a28c14e8c02/1603565365081/EGFR.jpg About - Targeting the Cancer Cells —Epidermal Growth Factor Receptor - EGFR - is overexpressed in many cancers including bladder cancers. —The EGF pathway and receptor play an important role in bladder cancer pathogenesis and proliferation. Aurora Oncology technology uses EGFR to target detection and target therapy in a novel way that only requires binding. Thus, the EGFR heterogeneity and the development of drug resistance that can thwart other EGFR pathway inhibition approaches is not a problem for our technologies https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f9476207203037f6287b3d8/1603565103927/Model.jpg About - Localizing Targeted Therapy EGFR is overexpressed on the luminal surface of bladder cancers —70% of urothelial cancers express EGFR while expression is rare in normal urothelium. Intravesical delivery of drugs into the bladder target EGFR expressing cancer cells while leaving healthy bladder cells unharmed. Delivery to the bladder also avoids or eliminates exposure to systemic circulation the potential for systemic toxicity. https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f9476af86c6207d28503a6e/1603565246549/ About - Targeting Detection Aurora is developing a non-invasive diagnostic test to detect over expressed EGFR from cancer cells in the urine to enable treating only those patients that will respond to EGFR-targeted therapy. Aurora is also developing and advanced theranostic approach that allows for unprecedented sensitivity in imaging early stage disease. EGFR-specific nanoparticals will allow detection of EGFR expressing cancer cells against a dark background with the subsequent ability to thermally ablate cells that have bound the particles. https://static1.squarespace.com/static/5f640537e0a19475b6919b2f/t/5f9aea5e3ada5f54efc0fef4/1603988074049/Picture1.png About https://www.auroraoncology.com/invest daily 0.75 2020-12-02 https://www.auroraoncology.com/news daily 0.75 2020-12-02